CANINE DISTEMPER VIRUS INFECTION LEADS TO AN INHIBITORY PHENOTYPE OF MONOCYTE-DERIVED DENDRITIC CELLS IN VITRO WITH REDUCED EXPRESSION OF CO-STIMULATORY MOLECULES AND INCREASED INTERLEUKIN-10 TRANSCRIPTION.

Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription.

Canine distemper virus (CDV) exhibits a profound lymphotropism that causes immunosuppression and increased susceptibility of affected dogs to opportunistic infections.Similar to human measles virus, CDV is supposed to inhibit terminal differentiation of dendritic cells (DCs), responsible for disturbed repopulation of lymphoid tissues and diminished

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Rockall and Hatton: Resolving a Super Wicked Marine Governance Problem in the High Seas of the Northeast Atlantic Ocean

The Hatton-Rockall plateau in the northeast Atlantic Ocean has long been the subject of interest for fishers, prospectors, conservationists, managers, planners, and politicians.As a feature that straddles national and international waters, it is subject to a multitude of competing and confounding regulations, making the development of a holistic ma

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Luminescence Dating of Rock Surface. The Case of Monoliths from the Megalithic Sanctuary of Ossimo-Pat (Valle Camonica, Italy)

Ossimo-Pat megalithic sanctuary (Valle Camonica, BS, Italy) is one of the most relevant archaeological findings of the southern alpine region, for the variety of its structures and the quality of its engraved monoliths.Its unique state of preservation gives the opportunity to apply the luminescence Neutral Cleaner dating of the rock surface method.

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